The Macintosh-compatible MacVector also offers multiple sequence analysis options and includes the AssemblyLIGN module to assemble consensus sequences. The UNIX-based package supports Web-based access via SeqWeb, and has a relational database version that integrates with SeqStore, the company's Oracle-based data management and mining system. What follows is a round up of each company's latest offerings.ĬORPORATE COMPENDIUM San Diego-based Accelrys' widely known GCG Wisconsin Package houses over 100 sequence analysis applications. DoubleTwist, supplier of TwistTools, has closed, and despite repeated efforts, we were unable to reach Gentech, Biotechnix3d's supplier, to confirm either the status of that program, or even if the company is still in business (its Web site has been under construction for some time). New companies on our list include ApoCom Genomics, Bioinformatics Solutions, and Paracel. Since our last review, (1) the software market has changed somewhat. Recently, companies have worked to make these programs user-friendly enough for anyone to use, often including detailed user manuals, get-started tutorials, and step-by-step protocol guides. Most are also Web-enabled, allowing users to download data from remote databases. Researchers install most programs locally, on a desktop computer, but some packages are Web-accessible. Some sequence analysis programs include a broad range of these functions, whereas others include individual, task-specific modules smaller labs with specialized needs may find that purchasing particular modules better fits their budgets. Yet they can each perform some or all of the following functions: DNA and protein sequence entry, editing, annotation, analysis, and alignment primer identification map making contig assembly "in silico" cloning and gel prediction. These programs vary in terms of ease-of-use, power, and functionality. In the world of bioinformatics, the need to examine and manipulate large volumes of sequence data begat specialized computer software to handle these tasks. Getting Started with MacVector: An overview of primer design workflows in MacVector.It is often said that necessity is the mother of invention.Melissa Caimano on HOW DO I video guides to common molecular biology workflows.admin on HOW DO I video guides to common molecular biology workflows.mariam abdelmalak on Major release details – Summary.Brian on Designing primers and documenting In-Fusion Cloning with MacVector.Chris on Designing primers and documenting In-Fusion Cloning with MacVector.How to call heterozygotes in trace files or Assembly Projects.MacVectorTip: How to Customize the Toolbars of MacVector windows. ![]()
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